Thresholds
5.1 The analysis should be quantitative to the point of being able to accurately verify
the threshold limits within the given tolerance.
5.2 In cases where compliance with acceptable limits, or lack thereof, is unclear,
additional sampling or other methodologies for sampling should be considered.
Tolerance range
5.3 Statistical reliability for each (compound-specific) brief sampling
procedure should be documented. The analysis should be quantitative to the point of
being able to accurately verify the threshold limits within the given tolerance. On the
basis of these data a compound-specific tolerance range should be derived and stated in
the method description. In general, the tolerance range should not be higher than the
standard deviation under typical conditions for testing and should under no
circumstances go beyond 30%.